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MOTS-C vs SS-31

MOTS-C and SS-31 are both stocked here and are often considered together. This page sets out what differs between them: their class, the sizes and price per milligram, the shape of the published evidence behind each, and where each stands under Canadian law. It does not rank them, because which is appropriate depends on what is being studied.

Side by side

MOTS-CSS-31
ClassMitochondrial-derived peptideMitochondria-targeting tetrapeptide (cardiolipin binder)
Sizes and price10 mg · 40 mg — from $42.00 (best $1.76/mg)10 mg — from $70.50 (best $7.05/mg)
Published evidence7 cited studies; 1 in people, none controlled.7 cited studies; 3 controlled trials in people.
Models studiedmouse, cell culture, rathuman, mouse
Status in CanadaNo Drug Identification NumberNo Drug Identification Number; named in a Health Canada advisory
Formatsvial, starter, valuevial, starter

Key differences

  1. MOTS-C 7 cited studies; 1 in people, none controlled. SS-31 7 cited studies; 3 controlled trials in people.

  2. No published study has compared MOTS-C and SS-31 directly. Everything above is drawn from separate studies of each compound, so the two columns are not results from one experiment.

  3. Both are supplied for in-vitro laboratory research only and neither is for human or veterinary use.

FAQ

What is the difference between MOTS-C and SS-31?

MOTS-C is mitochondrial-derived peptide; SS-31 is mitochondria-targeting tetrapeptide (cardiolipin binder). The table above sets out the sizes, the price per milligram, the evidence behind each and their Canadian status.

Which has more published research, MOTS-C or SS-31?

MOTS-C has 7 cited studies on its page and SS-31 has 7. Study count is not quality: the model each one used matters more, and both pages list that for every paper.

Are MOTS-C and SS-31 authorized in Canada?

No Drug Identification Number for MOTS-C. No Drug Identification Number; named in a Health Canada advisory for SS-31. Health Canada authorizes a drug by issuing an eight-digit Drug Identification Number, and most research peptides have none.

Can MOTS-C and SS-31 be used together?

No published study has tested them in combination, so there is no evidence about what a pairing does. We supply both for laboratory research and make no claim about using them together.