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Melanotan II vs PT-141

Melanotan II and PT-141 are both stocked here and are often considered together. This page sets out what differs between them: their class, the sizes and price per milligram, the shape of the published evidence behind each, and where each stands under Canadian law. It does not rank them, because which is appropriate depends on what is being studied.

Side by side

Melanotan IIPT-141
ClassNon-selective melanocortin receptor agonist (cyclic alpha-MSH analogue)Melanocortin receptor agonist (MC3R and MC4R; cyclic alpha-MSH analogue)
Sizes and price10 mg — from $43.00 (best $4.30/mg)10 mg — from $43.00 (best $4.30/mg)
Published evidence8 cited studies; 3 in people, none controlled.8 cited studies; 8 controlled trials in people.
Models studiedrat, mouse, zebrafishhuman
Status in CanadaNo Drug Identification Number; named in a Health Canada advisoryNo Drug Identification Number; named in a Health Canada advisory
Formatsvial, nasal, startervial, nasal, starter

Key differences

  1. Melanotan II 8 cited studies; 3 in people, none controlled. PT-141 8 cited studies; 8 controlled trials in people.

  2. No published study has compared Melanotan II and PT-141 directly. Everything above is drawn from separate studies of each compound, so the two columns are not results from one experiment.

  3. Both are supplied for in-vitro laboratory research only and neither is for human or veterinary use.

FAQ

What is the difference between Melanotan II and PT-141?

Melanotan II is non-selective melanocortin receptor agonist (cyclic alpha-msh analogue); PT-141 is melanocortin receptor agonist (mc3r and mc4r; cyclic alpha-msh analogue). The table above sets out the sizes, the price per milligram, the evidence behind each and their Canadian status.

Which has more published research, Melanotan II or PT-141?

Melanotan II has 8 cited studies on its page and PT-141 has 8. Study count is not quality: the model each one used matters more, and both pages list that for every paper.

Are Melanotan II and PT-141 authorized in Canada?

No Drug Identification Number; named in a Health Canada advisory for Melanotan II. No Drug Identification Number; named in a Health Canada advisory for PT-141. Health Canada authorizes a drug by issuing an eight-digit Drug Identification Number, and most research peptides have none.

Can Melanotan II and PT-141 be used together?

No published study has tested them in combination, so there is no evidence about what a pairing does. We supply both for laboratory research and make no claim about using them together.