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Melanotan I vs PT-141

Melanotan I and PT-141 are both stocked here and are often considered together. This page sets out what differs between them: their class, the sizes and price per milligram, the shape of the published evidence behind each, and where each stands under Canadian law. It does not rank them, because which is appropriate depends on what is being studied.

Side by side

Melanotan IPT-141
ClassMelanocortin-1 receptor agonist (linear alpha-MSH analogue)Melanocortin receptor agonist (MC3R and MC4R; cyclic alpha-MSH analogue)
Sizes and price10 mg — from $43.00 (best $4.30/mg)10 mg — from $43.00 (best $4.30/mg)
Published evidence8 cited studies; 1 controlled trial in people.8 cited studies; 8 controlled trials in people.
Models studiedhuman, cell culture plus human open-label pilot, rathuman
Status in CanadaIngredient appears in the Drug Product Database in other productsNo Drug Identification Number; named in a Health Canada advisory
Formatsvial, startervial, nasal, starter

Key differences

  1. Melanotan I 8 cited studies; 1 controlled trial in people. PT-141 8 cited studies; 8 controlled trials in people.

  2. No published study has compared Melanotan I and PT-141 directly. Everything above is drawn from separate studies of each compound, so the two columns are not results from one experiment.

  3. Both are supplied for in-vitro laboratory research only and neither is for human or veterinary use.

FAQ

What is the difference between Melanotan I and PT-141?

Melanotan I is melanocortin-1 receptor agonist (linear alpha-msh analogue); PT-141 is melanocortin receptor agonist (mc3r and mc4r; cyclic alpha-msh analogue). The table above sets out the sizes, the price per milligram, the evidence behind each and their Canadian status.

Which has more published research, Melanotan I or PT-141?

Melanotan I has 8 cited studies on its page and PT-141 has 8. Study count is not quality: the model each one used matters more, and both pages list that for every paper.

Are Melanotan I and PT-141 authorized in Canada?

Ingredient appears in the Drug Product Database in other products for Melanotan I. No Drug Identification Number; named in a Health Canada advisory for PT-141. Health Canada authorizes a drug by issuing an eight-digit Drug Identification Number, and most research peptides have none.

Can Melanotan I and PT-141 be used together?

No published study has tested them in combination, so there is no evidence about what a pairing does. We supply both for laboratory research and make no claim about using them together.